NIH Clinical Center Senior Staff
David A. Bluemke, MD, PhD, MsB, FAHA, FACR
Dr. Bluemke earned his medical degree at the University of Chicago's Pritzker School of Medicine as part of the Medical Scientist Training Program and his PhD from the University of Chicago's Department of Biophysics and Theoretical Biology, where he studied the evaluation of three-dimensional macromolecules using advanced computer modeling techniques. He also holds an undergraduate degree in chemical engineering from the University of Wisconsin-Madison and a Master of Science in business from Johns Hopkins University. His training includes a fellowship in cross-sectional imaging in diagnostic radiology at Johns Hopkins School of Medicine and residency at the Johns Hopkins Hospital. He is a fellow of the American Heart Association, American College of Radiology and the North American Society of Cardiovascular Imaging.
Dr. Bluemke's research focuses on cardiovascular disease and its complications and seeks to better understand especially how subclinical disease can be detected with newly developed imaging technologies, described, and tracked over time. His group was the first to describe the use of myocardial delayed enhancement in arrhythmogenic right ventricular dysplasia (ARVD), and the first to document quantitative evaluation of cardiac function in this condition, as well as normal variations of the geometry of the right heart. He was the principal investigator of the MRI reading center for the U.S. ARVD multi-center trial. Under Dr. Bluemke's direction, the Johns Hopkins Division of MRI was also one of the first groups to demonstrate a method for multi-station MRI angiography and for the intravascular assessment of ultra-high resolution evaluation of atherosclerotic plaque in humans. His area of expertise in imaging also extends to oncologic disease and the evaluation of cancer with MRI. Dr. Bluemke was a lead author on four large, multi-center clinical trials evaluating the use of novel contrast for MRI for oncologic applications, the largest multi-study of MRI in the evaluation of breast cancer, and a multi-center trial in cardiovascular disease. He is currently studying cardiovascular disease with MRI in the Epidemiology of Diabetes Interventions and Complications (EDIC) trial of more than 1000 type 1 diabetic patients and the Multi-Ethnic Study of Atherosclerosis (MESA) study of 6800 individuals. Ongoing NIH protocols include the study of patients with heart failure and hypertrophic cardiomyopathy using advanced imaging techniques.
Dr. Bluemke has shared this knowledge by teaching more than 50 post-graduate trainees from across North America and internationally in radiology and cardiology. He has also lectured at more than 200 international and national conferences, CME events, and society meetings.
He is a member of the board of trustees for the Internal Society of Magnetic Resonance in Medicine (ISMRM), board member of the North American Society of Cardiovascular Imaging and Society of Cardiovascular Magnetic Resonance, past chair of the American College of Radiology (ACR) Cardiac Accreditation Committee, and past program chair of the ISMRM Cardiac MR Study Group. He has been appointed to the American Heart Association Council on Radiology and Intervention, the ACR Committee on Standards for Body MRI, and the ACR Committee on Standards and Accreditation for Magnetic Resonance.
His most recent awards include the Margulis Award for best manuscript in Radiology (2014), an outstanding teacher award from ISMRM in cardiovascular imaging, the elite reviewer award from the Journal of the American College of Cardiology, two Executive Council awards and a silver medal from the American Roentgen Ray Society, and Cum Laude and contrast agent awards from the Society of Computed Body Tomography and Magnetic Resonance. In 2007 Dr. Bluemke was named among the top 10 radiologists by Medical Imaging and among America's Top Doctors by Castle Connolly Medical Ltd for the past 5 years. He has received two NIH Director's awards and the NIH Clinical Center Director's award.
To date, Dr. Bluemke has co-authored more than 520 peer-reviewed publications, 400 scientific abstracts, and 30 book chapters and monographs. The breadth of his writing reflects the range of his expertise in diagnostic radiology and parallels the tremendous technology changes in the fields of MRI and Computed Tomography. He has served on the editorial boards of several journals: the Journal of Computed Axial Tomography, Journal of Magnetic Resonance Imaging, Applied Radiology and the International Journal of Cardiovascular Imaging and a consultant to the editor for Radiology. He is a reviewer for more than 20 scientific journals, including the Journal of the American Medical Association and the New England Journal of Medicine.
Selected Journal Articles
Jain A, McClelland RL, Polak JF, Shea S, Burke GL, Bild DE, Watson KE, Budoff MJ, Liu K, Post WS, Folsom AR, Lima JA, Bluemke DA. Cardiovascular Imaging for Assessing Cardiovascular Risk in Asymptomatic Men Versus Women: The Multi-Ethnic Study of Atherosclerosis (MESA). Circ Cardiovasc Imaging. 2011 Jan 1;4(1):8-15. Epub 2010 Nov 10. PubMed PMID: 21068189.
Gai N, Turkbey EB, Nazarian S, van der Geest RJ, Liu CY, Lima JA, Bluemke DA. T(1) mapping of the gadolinium-enhanced myocardium: Adjustment for factors affecting interpatient comparison. Magn Reson Med. 2010 Dec 16. [Epub ahead of print] PubMed PMID: 21166021.
Chahal H, Johnson C, Tandri H, Jain A, Hundley WG, Barr RG, Kawut SM, Lima JA, Bluemke DA. Relation of cardiovascular risk factors to right ventricular structure and function as determined by magnetic resonance imaging (results from the multi-ethnic study of atherosclerosis). Am J Cardiol. 2010 Jul 1;106(1):110-6. Epub 2010 May 13. PubMed PMID: 20609657; PubMed Central PMCID: PMC2901248.
Fayad LM, Wang X, Salibi N, Barker PB, Jacobs MA, Machado AJ, Weber KL, Bluemke DA. A feasibility study of quantitative molecular characterization of musculoskeletal lesions by proton MR spectroscopy at 3 T. AJR Am J Roentgenol. 2010 Jul;195(1):W69-75. PubMed PMID: 20566784.
Nazarian S, Bluemke DA, Wagner KR, Zviman MM, Turkbey E, Caffo BS, Shehata M, Edwards D, Butcher B, Calkins H, Berger RD, Halperin HR, Tomaselli GF. QRS prolongation in myotonic muscular dystrophy and diffuse fibrosis on cardiac magnetic resonance. Magn Reson Med. 2010 May 17;64(1):107-114. [Epub ahead of print] PubMed PMID: 20572151.
El Khouli RH, Jacobs MA, Mezban SD, Huang P, Kamel IR, Macura KJ, Bluemke DA. Diffusion-weighted imaging improves the diagnostic accuracy of conventional 3.0-T breast MR imaging. Radiology. 2010 Jul;256(1):64-73. PubMed PMID: 20574085.
Barr RG, Bluemke DA, Ahmed FS, Carr JJ, Enright PL, Hoffman EA, Jiang R, Kawut SM, Kronmal RA, Lima JA, Shahar E, Smith LJ, Watson KE. Percent emphysema, airflow obstruction, and impaired left ventricular filling. N Engl J Med. 2010 Jan 21;362(3):217-27. PubMed PMID: 20089972.
Turkbey EB, McClelland RL, Kronmal RA, Burke GL, Bild DE, Tracy RP, Arai AE, Lima JA, Bluemke DA. The impact of obesity on the left ventricle: the Multi-Ethnic Study of Atherosclerosis (MESA). JACC Cardiovasc Imaging. 2010 Mar;3(3):266-74. PubMed PMID: 20223423.
Jain A, Shehata ML, Stuber M, Berkowitz SJ, Calkins H, Lima JA, Bluemke DA, Tandri H. Prevalence of Left Ventricular Regional Dysfunction in Arrhythmogenic Right Ventricular Dysplasia: A Tagged MRI Study. Circ Cardiovasc Imaging. 2010 Mar 2. [Epub ahead of print] PubMed PMID: 20197508.
Liu CY, Redheuil A, Ouwerkerk R, Lima JA, Bluemke DA. Myocardial fat quantification in humans: Evaluation by two-point water-fat imaging and localized proton spectroscopy. Magn Reson Med. 2010 Apr;63(4):892-901. PubMed PMID: 20373390.
Jain A, Tandri H, Dalal D, Chahal H, Soliman EZ, Prineas RJ, Folsom AR, Lima JA, Bluemke DA. Diagnostic and prognostic utility of electrocardiography for left ventricular hypertrophy defined by magnetic resonance imaging in relationship to ethnicity: the Multi-Ethnic Study of Atherosclerosis (MESA). Am Heart J. 2010 Apr;159(4):652-8. PubMed PMID: 20362725; PubMed Central PMCID: PMC2856691.