Clinical Center News
March 2016

NIH scientists discover genetic cause of rare allergy to vibration

Scientists at the National Institutes of Health have identified a genetic mutation responsible for a rare form of inherited hives induced by vibration.
Scientists at the National Institutes of Health have identified a genetic mutation responsible for a rare form of inherited hives induced by vibration.
 

Scientists at the NIH have identified a genetic mutation responsible for a rare form of inherited hives induced by vibration, also known as vibratory urticaria. Running, hand clapping, towel drying or even taking a bumpy bus ride can cause temporary skin rashes in people with this rare disorder. By studying affected families at the NIH Clinical Center, researchers discovered how vibration promotes the release of inflammatory chemicals from the immune system's mast cells, causing hives and other allergic symptoms.

Their findings, published online in the New England Journal of Medicine on Feb. 3, suggest that people with this form of vibratory urticaria experience an exaggerated version of a normal cellular response to vibration. The study was led by researchers at the National Institute of Allergy and Infectious Diseases (NIAID) and the National Human Genome Research Institute (NHGRI), both part of NIH.

Read more in the NIH press release online.

Stories
Senior leaders at NIH cut a ribbon opening two hospice suites at the Clinical Center
Laptop with stethoscope nearby
Patient Photography Studio
Dr. Francis Collins, director of the NIH sties in a chair to the left. Barbra Streisand holds a microphone and sits in a chair to the right – speaks to the audience
Dr. James Gilman stands with Alba C. Murphy as they smile and hold a certificate
A paper cutout of a hand shape with a stick on the end. Text on the paper says I [heart] clean hands
Patient with Degos disease addresses symposium attendees
CDC and NIH representatives stand in a special isolation patient room at the NIH Clinical Center
Eight young men and women line up holding graduation certificates in Lipsett Auditorium
A four panel exhibit with photos, text and artifacts on NIH medical pioneers Christian Anfinsen and Michael Potter
NIH Clinical Center volunteer Chaoyang Wang
Woman with scientific cap on her head plays a touch game
Doctors at NIH speak in a lecture hall during Nurses Week
NIH Clinical Center doctor receives award
Children participate in Take Your Child to Work Day Hematology Lab
Leslie Wehrlen holds a plaque.
Sixteen women, graduates of the program and departmental leaders, gather for a photo
Pius Aiyelawo swearing into the Senior Executive Service with Dr. Lawrence Tabak
Jackson Taylor (right) and his donor Sean McLaughlin (left)
Dr. Thomas Burklow
Two care providers look at a computer
Child reading a book
NIH employee, Ricky Day, trys the prototype device
U.S. Surgeon General Dr. Jerome Adams tours Clinical Center with CC CEO Dr. James K. Gilman
First Lady Melania Trump gets together with five children to pose for a picture
Patient and doctor
Harold Varmus, Robert Frasca, Mark Hatfield and John Gallin at the groundbreaking of the hospital's new addition
Black and White photo of the first meeting of the National Advisory Eye Council (13 men) gathering on steps
Jim Gilman at Town Hall in Masur Auditorium
Martha Rinker, speaker from the non-profit National Organization for Rare Disorders (NORD), addresses the audience on Rare Disease Day Feb. 29, 2016, at the NIH Clinical Center.
Betsy Furlong inspects the UV Illuminator cassette.
In January 2016, Dr. Robert Watcher visited the NIH and presented at a Contemporary Clinical Medicine: Great Teachers Lecture.
Scientists at the National Institutes of Health have identified a genetic mutation responsible for a rare form of inherited hives induced by vibration.
The atrium gift shop recently re-opened under management of the Foundation for the Advancement of Education in the Sciences
Avish Parashar brought audience members on stage to showcase that planning is important, but the ability to improvise is essential during a seminar on Dec. 3.
The open forum of the town hall provided an opportunity for staff to learn about Building 10 updates and offer input.
Dr. Pete Choyke discusses his research with fifteen members of the Oncology Nursing Society.
Everyone who works in the Clinical Center, in every type of occupation, can provide feedback in the 2016 NIH Clinical Center Employee Survey.
Israeli Minister of Health MK Rabbi Yacov Litznan visits the NIH Clinical Center.
Dr. Richard W. Childs, joined by his wife, son and daughter, says the oath of office.
Parking booth attendants decorated their facilities to show holiday cheer.
Dr. John I. Gallin presents Dr. Clare Hastings with the 'dirt award' at her retirement gathering.
About 300 awards were presented at the Clinical Center Director's Annual Address and Awards Ceremony on Dec. 18.
Rebecca Vichi, Clinical Center volunteer.
Dr. John I. Gallin cuts the ribbon with Heidi Grolig and Jerry Sachs.
Picture of woman looking at camera.
People line up at the new marketplace Starbucks café