Clinical Center News
May / June 2024

Clinical trials at NIH Clinical Center in need of participants

Researchers at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) seek volunteers 18-60 years old to participate in a study examining how processed and unprocessed food affects metabolic health. Compensation is provided.

Contact the NIH Clinical Center Office of Patient Recruitment at 866-444-2214 (TTY users dial 7-1-1) or ccopr@nih.gov. Refer to study #22-DK-0002. https://go.usa.gov/xJxDr.

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Systemic lupus erythematosus (SLE) is a chronic (long-lasting) autoimmune disease that can affect many body parts. Lupus occurs when the immune system, which usually helps protect the body from infection and illness, attacks its own tissues. This attack causes inflammation and, in some cases, permanent tissue damage, which can be widespread – affecting the skin, joints, heart, lungs, kidneys, circulating blood cells, and brain. Approximately 1.5 million Americans have a form of lupus, and of these 90% are women. In a recent study, two investigators at the NIH combined their expertise in lupus and inflammation to explore the effects of exposing blood cells from lupus patients to the dietary supplement nicotinamide riboside (NR) in the lab and found it had positive effects on inflammation in the cells (Wu et al). Now in a new study#001621, "Pilot Study to Evaluate the Effect of NAD+ Boosting with Nicotinamide Riboside on Immunometabolism and Immunity in Systemic Lupus Erythematosus," these researchers will look at the effect on the immune system of taking nicotinamide riboside (NR) versus a placebo pill on patients with lupus. They will also look at changes in blood vessel elasticity, a marker of increased risk for coronary artery disease in patients with lupus. Participating in this research study may be a great opportunity for those who suffer from lupus. In addition, the team is seeking healthy volunteers to participate in research that may help lupus patients with better treatment for their conditions. Blood samples from participating healthy volunteers will be used to compare with blood from patients with lupus. Healthy volunteers will generally only have one visit during participation. To join this study, contact the NIH Clinical Center Office of Patient Recruitment at 866-444-2214 (TTY users dial 7-1-1) or ccopr@nih.gov. NIH Study #001621-H. https://go.nih.gov/GyIFtVv.

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In health care, AI can pick up subtle changes in speech that can offer information about your health, such as an illness like the common cold. However, only some conditions can be detected with traditional AI techniques. There is still work ahead in making modern technology like AI more accurate for healthcare applications. The NIH Clinical Center is conducting a study by collecting voice samples from healthy and diagnosed individuals answering questions about their health. The aim is to design a new type of AI model to accurately diagnose various diseases.

Join the NIH by providing a voice sample on an online web-based app. For questions, call the NIH Clinical Center Office of Patient Recruitment at 1-800-411-1222 and ask for information on research study #IRB001596.

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