Search by Department


Additional NIH Doctors/Researchers

Meet Our Doctors


Dr. Caroline E. Nottingham
Caroline E. Nottingham, PhD, DABCC

Staff Scientist
Director, Mass Spectrometry, Urinalysis and STAT Laboratory


Laboratory Medicine


BS, UNC Wilmington
PhD, University of Virginia


Phone:301-496-3453

Dr. Caroline E. Nottingham
Caroline E. Nottingham, PhD, DABCC

Staff Scientist
Director, Mass Spectrometry, Urinalysis and STAT Laboratory


Laboratory Medicine


BS, UNC Wilmington
PhD, University of Virginia


Phone:301-496-3453


Dr. Caroline E. Nottingham is a board-certified Clinical Chemist in the Department of Laboratory Medicine at the NIH Clinical Center.


Dr. Nottingham received her PhD from the University of Virginia, where her research focused on the development of novel mass spectrometry-based assays for detection of protein and lipid kinase activity. She then completed her Clinical Chemistry Fellowship training at the Washington University School of Medicine in St. Louis. She is board-certified in Clinical Chemistry through the American Board of Clinical Chemistry.

In 2021, she joined the Chemistry Faculty in the Department of Laboratory Medicine at the NIH Clinical Center. She currently oversees the Mass Spectrometry, Urinalysis and STAT Laboratory sections in the DLM Chemistry Service.

Franks CE, Li J, Martinez M, Farnsworth CW, Jones PM, Grenache DG, Meng QH, Gronowski AM. Utility of commercially available quantitative hCG immunoassays as tumor markers in trophoblastic and non-trophoblastic disease. Clin Chem 2023;69(6):606-614.

Tawiah KD, Franks CE, Tang J, Gazit A, Dietzen D, Farnsworth CW. Comparison between BNP and NT-proBNP in pediatric populations. Clin Biochem 2022;109-110:74-78.

Franks CE, Gronowski AM. The faces of women in AACC - a historical reflection on AACC leadership and awards. Clin Chem 2021;67(2):449-453.

Franks CE, Scott MG. On the basis of race: the utility of a race factor in estimating glomerular filtration. JALM 2021;6(1):155-166.

Franks CE, Krekeler JA, Gronowski AM, Farnsworth CW. A comparison of four 3-axis-accelerometers for monitoring hospital pneumatic tube systems. JALM 2020;5(6):1345-1350.

Franks CE, Scott, MG, Farnsworth CW. Elevated Cardiac Troponin I Is Associated with poor outcomes in COVID-19 patients at an academic medical center in midwestern USA. JALM 2020;5(5):1137-1139.

Ware TB, Franks CE, Granade ME, Zhang M, Kim KB, Park KS, Gahlmann A, Harris TE, Hsu KL. Reprogramming fatty acyl specificity of lipid kinases via C1 domain engineering. Nat Chem Biol 2020;16:170-178.

Franks CE, Hsu KL. Activity-based kinome profiling by ATP acyl phosphate probes. Current Protocols Chemical Biology 2019;11:e72.

Shin M, Franks CE, Hsu KL. Isoform-selective activity-based profiling of ERK signaling. Chem Sci 2018;9:2419-2431.

Franks CE, Campbell ST, Purow BW, Harris TE, Hsu KL. The ligand binding landscape of diacylglycerol kinases. Cell Chem Biol 2017;24:870-880.


  • NIH Clinical Center CEO Award, 2022
  • Clinical Chemistry Diplomate, American Board of Clinical Chemistry, 2022
  • The Jack Ladenson Chief Clinical Chemistry Fellow, Washington University School of Medicine, 2020
  • Sidney M. Hecht Graduate Fellow, University of Virginia, 2018
  • University Honors with Honors in Chemistry, UNC Wilmington, 2014

NOTE: PDF documents require the free Adobe Reader.

This page last updated on 04/01/2024

You are now leaving the NIH Clinical Center website.

This external link is provided for your convenience to offer additional information. The NIH Clinical Center is not responsible for the availability, content or accuracy of this external site.

The NIH Clinical Center does not endorse, authorize or guarantee the sponsors, information, products or services described or offered at this external site. You will be subject to the destination site’s privacy policy if you follow this link.

More information about the NIH Clinical Center Privacy and Disclaimer policy is available at https://www.cc.nih.gov/disclaimers.html