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Dr. Jeffrey R. Strich is a Staff Clinician in the Critical Care Medicine Department at the NIH Clinical Center.
Dr. Strich received his undergraduate degree from the University of Connecticut in Molecular and Cell Biology, his degree in Medicine from the Uniformed Services University of the Health Sciences, and his Masters in Health Services in Clinical Research from the Duke University School of Medicine. He completed residency training in Internal Medicine at Georgetown University Hospital and then completed a combined fellowship in Critical Care Medicine and Infectious Diseases at the National Institutes of Health.
His primary research interests are epidemiology, diagnosis, and treatment of highly resistant gram-negative infections and bacterial sepsis in critically ill patients. As part of the NIH Antimicrobial Resistance Outcomes Research Initiative (NIH–ARORI) he has used large datasets to track the uptake and utilization of novel gram-negative antibiotics and estimate the market size for future novel gram-negative antibiotics. He has developed liquid chromatography tandem mass spectrometry-based assays for the detection or antibiotic resistance proteins including the OXA-48 family, NDM, and MCR-1. Currently, he is developing a non-human primate model of Klebsiella pneumoniae septic shock with the goal of studying the host-pathogen interaction and novel treatments for antibiotic resistant gram-negative infections. Additionally, he has an interest in the clinical and immunological characterization and treatment of emerging pathogens including SARS-CoV-2.
Dr. Strich is a Medical Officer in the United States Public Health Services Commissioned Corps. Prior to pursuing his degree in Medicine he served as a Special Assistant in the Office of the Surgeon General.
Dr. Strich is a member of the Infectious Disease Society of America (IDSA) where he serves as the IDSA Sepsis Task Force Executive Secretary and is a member of the Society of Critical Care Medicine. He holds an appointment as an Adjunct Assistant Professor of Medicine at the Uniformed Services University of the Health Sciences.
Strich JR, Warner S, Lai YL, Demirkale CY, Powers JH 3rd, Danner RL, Kadri SS. Needs assessment for novel Gram-negative antibiotics in US hospitals: a retrospective cohort study. Lancet Infect Dis. 2020 Jun 4; S1473-3099(20)30153-5.
Strich JR, Warner S, Lai YL, Demirkale C, Powers JH, Danner RL, Kadri, SS. Needs assessment for novel Graam-negative antibiotic in US Hospitals: a retrospective cohort study. Lancet Infect Dis. 2020 May 6.
Strich JR, Ricotta E, Warner S, Demirkale CY, Hohmann SF, Rhee C, Klompas M, Palmore T, Powers JH, Dekker JP, Adjemian J, Matsouaka R, Woods CW, Danner RL, Kadri SS. Pharmacoepidemiology of Ceftazidime-avibactam Use: A Retrospective Cohort Analysis of 210 US Hospitals. Clin Infec Dis. 2020 Feb 28.
Strich JR, Kadri SS. Difficult-to-Treat Antibiotic Resistant Gram-Negative Pathogens in the Intensive Care Unit: Epidemiology, Outcomes, and Treatment. Semin Respir Crit Care Med. 2019 Aug;40(4):419-434.
Strich JR, Wang H, Cisse OH, Youn JH, Drake SK, Chen Y, Rosenberg AZ, Gucek M, McGann PT, Dekker JP, Suffredini AF. Identification of OXA-48 Carbapenemase Family Using Tryptic Peptides and LC-MS/MS. J Clin Microbiol 2019, Feb 27.
Strich JR, Chertow DS. CRISPR-Cas Biology and Infectious Disease Applications. J Clin Microbiol. 2019 Mar 28;57(4)
Kadri SS, Rhee C, Strich JR, Morales M, Hohmann S, Menchaca J, Suffredini A, Danner R, Klompas M. Estimating Ten-Year Trends in Septic Shock Incidence and Mortality in United States Academic Medical Centers Using Clinical Data. Chest. 2017. 151(2):278-285
- USPHS Commendation Medal, 2020
- USPHS Commendation Medal, 2019
- USPHS Unit commendation, 2019
- NIH Clinical Center CEO Award, 2018
- USPHS Presidential Unit Citation, 2016
- Eric Lemmer Memorial Research Award, 2015
- USPHS PHS Achievement Medal, 2013
- USPHS PHS Citation, 2010
- USPHS PHS Citation, 2008
- USPHS PHS Unit Commendation, 2008
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This page last updated on 05/17/2021