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Dr. Sameer S. Kadri is currently an associate research physician and head of the Clinical Epidemiology Section in the Clinical Center's Critical Care Medicine Department.
Dr. Kadri earned his degree in Medicine from the Seth G. S. Medical College and King Edward Memorial Hospital in Mumbai, India. He went on to complete internship and residency training in Internal Medicine at the New York-Presbyterian Hospital and Weill Cornell Medical Center and obtained a Masters degree in Clinical Epidemiology at the Harvard T.H. Chan School of Public Health.
Following his fellowship training in Critical Care Medicine at the NIH and in Infectious Diseases at Massachusetts General Hospital and Harvard Medical School, Dr. Kadri was appointed to Staff Clinician in the Critical Care Medicine Department at the NIH in 2014. In this role, he splits his time between attending in the Intensive Care Unit at the NIH Clinical Center, conducting clinical research and training clinical and research fellows in the Critical Care Medicine Department.
His primary research interest lies in infections in the critically ill. He leverages large datasets for epidemiologic investigations on antimicrobial resistance, sepsis, procalcitonin use, smoke inhalation acute lung injury and the role of IVIG in necrotizing fasciitis and granulocyte transfusions in invasive mycoses. His ongoing work includes use of large electronic health record-based repositories to understand the market size for new antibiotics (in collaboration with the US FDA), the impact of early discontinuation of antibiotics in culture negative sepsis and identify more objective candidate ICU performance measures.
He founded and leads the NIH Antimicrobial Resistance Outcomes Research Initiative (NIH–ARORI), a collaborative between the NIH Clinical Center, Intramural NIAID, the CDC and Harvard Medical School. Through this initiative he developed and tested a simple but clinically relevant bedside classification scheme for antimicrobial resistance called “Difficult-to-treat Resistance” or DTR that focuses on non-susceptibility to all first-line antibiotics. He is a peer reviewer for several subspecialty journals and has served as an editor for the Infectious Diseases Clinics of North America issue titled Complex Infectious Disease Issues in the Intensive Care Unit. He has spearheaded investigations that underscore the benefits of dually training in critical care medicine and infectious diseases and is promoting the unique role of critical care providers in combating antimicrobial resistance.
Kadri SS, Adjemian J, Lai YL, et al. Difficult-to-Treat Resistance in Gram-negative Bacteremia at 173 US Hospitals: Retrospective Cohort Analysis of Prevalence, Predictors, and Outcome of Resistance to All First-line Agents. Clin Infect Dis. Published online: July 2018
Kadri SS. Recognizing the Unique Role of Critical Care Providers in Confronting Antimicrobial Resistance. Am J Respir Crit Care Med 2018 Jun 25.
Kadri SS, Swihart BJ, Bonne SL, et al. Impact of Intravenous Immunoglobulin on Survival in Necrotizing Fasciitis with Vasopressor-Dependent Shock: A Propensity Score-Matched Analysis From 130 US Hospitals. Clin Infect Dis 2017 Apr 1;64(7):877-885
Kadri SS, Rhee C, Strich JR Synergy, Salary, and Satisfaction: Benefits of Training in Critical Care Medicine and Infectious Diseases Gleaned from a National Pilot Survey of Dually Trained Physicians. Clin Infect Dis. 2016 Oct 1;63(7):868-875.
Kadri SS, Rhee C, Strich JR, et al. Estimating Ten-Year Trends in Septic Shock Incidence and Mortality in United States Academic Medical Centers Using Clinical Data. Chest 2017 Feb;151(2):278-285
Kadri SS, Miller AC, Hohmann S, et al. Risk factors for in-hospital mortality in smoke inhalation-associated acute lung injury: Data from 68 United States hospitals. Chest. 2016 Dec;150(6):1260-1268
Kadri SS, Rhee C, Fortna GS, O'Grady NP. Critical Care Medicine and Infectious Diseases: An Emerging Combined Subspecialty in the United States. Clin Infect Dis. 2015 Aug 15;61(4):609-14.
Kadri SS, Hohmann SF, Orav EJ, et al. Tracking colistin-treated patients to monitor the incidence and outcome of carbapenem-resistant Gram-negative infections. Clin Infect Dis. 2015 Jan 1;60(1):79-87
Levine AR and Kadri SS. Infectious Diseases – Empiric and Emergency Treatment in Critical Care Handbook of the Massachusetts General Hospital, 6th Edition. Philadelphia, Lippincott, Williams & Wilkins, 2015.
Bonne SL, Kadri SS. – Evaluation and Management of Necrotizing Soft Tissue Infections in Complex Infectious Disease Issues in the Intensive Care Unit Infect Dis. Clinic North America Volume 31, Issue 3, 1st Edition, Elsevier, 2017.
- 2018 Society of Critical Care Medicine Star Research Gold Medal Award
- 2018 NIH Clinical Center CEO Award for Clinical Epidemiology Research
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This page last updated on 01/21/2022