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Dr. Sandhya R. Panch is the medical director for the Center for Cellular Engineering in the NIH Clinical Center’s Department of Transfusion Medicine.
Dr. Panch received her medical degree from Bangalore Medical College, India. Subsequently, she obtained a Master’s in Public Health at the University of Minnesota and a residency in Internal Medicine from Georgetown University Hospital/Washington Hospital Center.
At the National Heart, Lung and Blood Institute, she was recruited into the Elaine M. Sloand joint fellowship program in Hematology/Oncology and Transfusion Medicine. She completed a post-doctoral training in molecular hematopoiesis under Cynthia E. Dunbar, at NHLBI prior to joining the NIH Clinical Center's Department of Transfusion Medicine as the medical director for the Center for Cellular Engineering in 2016.
Her research interests include the clinical and translational study of hematopoietic stem cell ontogeny, mobilization and expansion techniques and gene based therapies.
She is an active participant in the CIBMTR donor health and safety committee. She is also lead/associate investigator on several NIH-sponsored clinical and translational studies, with over 40 peer reviewed publications, book chapters, invited lectures and presentations in the areas of Hematology/Oncology, Transfusion Medicine, Bone Marrow Transplantation and Cell Therapies.
Currently, she serves as a guest editor for Seminars in Hematology, and as a peer reviewer for the Biology of Blood and Marrow Transplantation, Transfusion, Bone Marrow Transplantation, Journal of Translational Medicine, and the Journal of Clinical Apheresis. She also directs training and educational activities for clinical fellows, researchers and blood banking technologists in the CCE and provides ad-hoc consultation on the hematology clinical consult service at the NIH.
Panch SR, Bikkani T, Vargas V, Procter J, Atkins JW, Guptill V, Frank KM, Lau AF, Stroncek DF. A Prospective Evaluation of a Practical Guideline for Managing Positive Sterility Test Results in Cell Therapy Products. Biol Blood Marrow Transplant. 2018 Aug 8. PMID: 30098394
Panch SR, Bozik ME, Brown T, Makiya M, Prussin C, Archibald DG, Hebrank GT, Sullivan M, Sun X, Wetzler L, Ware J, Fay MP, Dunbar CE, Dworetzky SI, Khoury P, Maric I, Klion AD. Dexpramipexole as an Oral Steroid-sparing Agent in Hypereosinophilic Syndromes. Blood. 2018 PMID: 29739754.
Tageja N, Korde N, Kazandjian D, Panch S, Manasanch E, Bhutani M, Kwok M, Mailankody S, Yuan C, Stetler-Stevenson M, Leitman SF, Sportes C, Landgren O. Combination therapy with carfilzomib, lenalidomide and dexamethasone (KRd) results in an unprecedented purity of the stem cell graft in newly diagnosed patients with myeloma. Bone Marrow Transplant. 2018 PMID: 29728700.
Yu KR, Espinoza DA, Wu C, Truitt L, Shin TH, Chen S, Fan X, Yabe IM, Panch S, Hong SG, Koelle S, Lu R, Bonifacino A, Krouse A, Metzger M, Donahue RE, Dunbar CE. The impact of aging on primate hematopoiesis as interrogated by clonal tracking. Blood. 2018 Mar PMID: 29295845
Panch SR, Szymanski J, Savani B, Stroncek DF. Sources of Hematopoietic stem cells and methods to optimize yields for clinical cell therapy: Biology of Blood and Marrow Transplantation 2017 May; Review. PubMed PMID: 28495640
Beaulieu GP, Ward D, Panch SR, Flegel WA. Acanthocytes in the McLeod phenotype of X-linked chronic granulomatous disease (CGD) (In press). Transfusion 2017. Ms. No. Trans-2016-0599.R1
Panch SR, Yau YY, Fitzhugh CD, Hsieh MM, Tisdale JF, Leitman SF. Hematopoietic progenitor cell mobilization is more robust in healthy African American compared to Caucasian donors and is not affected by the presence of sickle cell trait. Transfusion. 2016 May;56(5):1058-65
Panch SR, Yau YY, West K, Diggs K, Sweigart T, Leitman SF. Initial serum ferritin predicts number of therapeutic phlebotomies to iron depletion in secondary iron overload. Transfusion. 2015 Mar;55(3):611-22.
Panch SR, Yau YY, Kang EM, De Ravin SS, Malech HL, Leitman SF. Mobilization characteristics and strategies to improve hematopoietic progenitor cell mobilization and collection in patients with chronic granulomatous disease and severe combined immunodeficiency. Transfusion. 2015 Feb;55(2):265-74.
Panch SR, Riordan MM, Miranda SJ, Leitman SF. Intermittent leukocytosis in an asymptomatic platelet donor. Transfusion. 2013 May;53(5):1144-6.
Ghosh SK, Chakaravarthy P, Panch SR, Krishnappa P, Tiwari S, Ojha VP, Manjushree R, Dash AP. Comparative efficacy of two poeciliid fish in indoor cement tanks against chikungunya vector Aedes aegypti in villages in Karnataka, India. BMC Public Health. 2011 Jul 28;11:599
John R, Panch S, Hrabe J, Wei P, Solovey A, Joyce L, Hebbel R. Activation of endothelial and coagulation systems in left ventricular assist device recipients. Ann Thorac Surg. 2009 Oct; 88(4):1171-9.
Panch SR, Klein HG. Book Chapter: Chapter 119. “Hemapheresis” Hoffman Hematology: Basic Principles and Practice, 7th edition, 2016
Panch SR, Bolan CD, Leitman SF. Book Chapter: Chapter 25. “Hemochromatosis” Bethesda Handbook of Clinical Hematology, 3rd edition, 2017
- American Society of Hematology, Medical Educators’ Program Participant Award, 2018
- National Blood Foundation early career award, American Association of Blood Banks, 2016
- AABB-Fenwal Scholarship Award for outstanding manuscript based on original research in transfusion medicine, Fellowship, NIHCC DTM, American Association of Blood Banks, 2014
- NHLBI Director’s Award for external scientific recognition, 2013
- AABB-Fenwal Scholarship Award for outstanding manuscript based on original research in transfusion medicine, Fellowship, NIHCC DTM, American Association of Blood Banks, 2013
- J B Hawley Student Research Grant: IGF-1, IGF-2 and IGF-BP levels in neonatal blood spots: correlation with birth weight and gestational age, University of Minnesota, 2008
- The Dean’s Scholarship, Master’s in Public Health, University of Minnesota, 2006
- Bharat Petroleum Scholarship Award, Master’s in Epidemiology and Clinical Research, Bharat Petroleum Pvt. Ltd. Mumbai, India, 2006
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This page last updated on 03/14/2019