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Patient Recruitment

Patients with Unresectable Fibrolamellar Hepatocellular Carcinoma (FLC)

Antibiotic Vancomycin

medical illustration of a human liver

close-up of a human liver

Researchers at the National Institutes of Health are studying the use of an antibiotic called vancomycin treatment for unresectable Fibrolamellar Hepatocellular Carcinoma (FLC). FLC most often occurs in young people who have no history of liver disease. Researchers think gut bacteria may affect liver cancer, this antibiotic will help alter the gut bacteria and may be beneficial for this type of cancer.

Study Design

  • Medical history and physical exam
  • Take vancomycin 3 times a day
  • Keep a medication diary
  • Have a liver biopsy before treatment
  • Follow-up visit a month after treatment

Who Can Particpate

  • Patients age 18 years or older
  • Diagnosed with unresectable Fibrolamellar Hepatocellular Carcinoma
  • Patient unresponsive to previous treatment

Location: The NIH Clinical Center, America's Research Hospital is located on the Metro red line (Medical Center stop) in Bethesda, Maryland.

For more information:
NIH Clinical Center Office of Patient Recruitment
800-877-8339 TTY / ASCII
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Or go online:
Refer to study # 19-C-0125

Department of Health and Human Services
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

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This page last updated on 02/25/2020

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