Skip to main content

Patient Recruitment Home

Current Protocols

Ethics in Clinical Research

Privacy Notice

FAQ About Clinical Studies

Contact Us

Call the Office of Patient Recruitment at 800-411-1222 to speak with one of our Information Specialists.

For those who are deaf, hard-of-hearing, or speech impaired, the Federal Relay Service provides free telecommunications relay services (TRS).

Se habla español.

Patient Recruitment

Trial of MVA-BN-Brachyury Vaccine in Patients with Advanced Cancer

a syringe inserted into a vial

patient and a family member

Researchers at the National Institutes of Health are testing the safety of MVA-BN-Brachyury vaccine for adults who have advanced metastatic cancer. The vaccine is designed to target cells responsible for tumor growth. Researchers hope the vaccine will help the immune system kill tumor cells and slow down cancer growth. If you have recurring advanced metastatic cancer that is not surgically removable and standard therapies have not been effective, you may be eligible to participate.

You can participate if you:

  • Are 18 years of age or older
  • Have an advanced metastatic cancer that has spread to other parts of the body
  • Have had failed standard therapies
  • Have no evidence of being immunocompromised
  • Are not pregnant or breastfeeding

Study design includes:

  • Complete physical exam and medical history
  • Blood and urine tests
  • Imaging, such as CT scans or MRIs
  • Electrocardiogram (EKG or ECG)
  • Vaccine during weeks 1, 4, and 7 with at least 2 nights of hospitalization after each vaccine
  • Follow-up visits 1 month and 3 months after last dose of vaccine
  • Financial assistance with travel and lodging provided

The NIH Clinical Center is America's Research Hospital and is located in Bethesda, Maryland, on the Metro Red line (Medical Center stop).

For more information:
NIH Clinical Center
Office of Patient Recruitment
800-411-1222 (refer to study # 20-C-0001)
800-877-8339 TTY / ASCII
Se habla español
Email: prpl@cc.nih.gov

Or go online:
https://go.usa.gov/xp6g6

Department of Health and Human Services
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

NOTE: PDF documents require the free Adobe Reader.

This page last updated on 03/10/2020

You are now leaving the NIH Clinical Center website.

This external link is provided for your convenience to offer additional information. The NIH Clinical Center is not responsible for the availability, content or accuracy of this external site.

The NIH Clinical Center does not endorse, authorize or guarantee the sponsors, information, products or services described or offered at this external site. You will be subject to the destination site’s privacy policy if you follow this link.

More information about the NIH Clinical Center Privacy and Disclaimer policy is available at http://www.cc.nih.gov/disclaimers.html