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Patient Recruitment

Do You Know Someone Diagnosed With Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)?

close-up of cells

3d rendered medically accurate illustration of too many white blood cells due to leukemia

Researchers at the National Institutes of Health (NIH) in Bethesda, Maryland are conducting an investigational treatment study with duvelisib to treat patients with ibrutinib-resistant CLL/SLL.

Eligible volunteers must be currently receiving ibrutinib for CLL/SLL and have BTK and/or PLCG2 mutations or progressive CLL/SLL. Compensation for travel may be provided.

Study Design:

  • One to two visits to the NIH Clinical Center in Bethesda, Maryland before enrolling into the protocol followed by clinic visits.
  • Clinic visits every 28 days for 6 cycles and every 3 months thereafter.
  • Patients will take duvelisib and ibrutinib for 6-months followed by duvelisib alone.
  • Treatment and follow up will continue indefinitely until disease progression or if intolerable side effects occur.
  • All study-related tests and procedures are provided at no cost.

Who Can Participate?

  • Patients 18 years or older diagnosed with CLL/SLL
  • Patients willing to use birth control for the duration of the study.
  • Patients willing to participate in all required evaluations and procedures in this study including swallowing capsules without difficulty.

Location: The NIH Clinical Center, America's Research Hospital is located on the Metro red line (Medical Center stop) in Bethesda, Maryland.

For more information:
NIH Clinical Center Office of Patient Recruitment
800-411-1222
800-877-8339 TTY / ASCII
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Email: PRPL@cc.nih.gov

Or go online:
https://go.usa.gov/xdTQU
Refer to study # 20-H-0016

Department of Health and Human Services
National Institutes of Health Clinical Center (CC)
National Heart, Lung and Blood Institute (NHLBI)

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This page last updated on 02/25/2020

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